If You Want To Block Any USB Devics In Your Computer Then Here Is A Simple Trick With Registry. Please Do It With Carefully.
1. Go To Start Menu And Click Run, Type Regedit.
2. Go To HKEY_LOCAL_MACHINE\System\Current ControlSet\Services\USBStor.
3. In The Rught Pane, Look For Value Start And Have Value As 0000000(3)
4. Double Click On ThatAnd Change Its Value To 4.
5. Now Restart Your PC And You Have Done With It, USB Is Blocked.
If You Want To Unblock Your USB Than Change Its Value Back To 3.